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Peptides
5 min read
Short answer. Appendix A lists BPC-157, epitalon, KPV, MOTS-c, semax, and TB-500 [2]. If a peptide is not on that list, this policy does not describe enforcement discretion for it. As of Oct 29, 2026.
Not on Appendix A
The policy does not name sermorelin, DSIP (emideltide), GHK-Cu, CJC-1295, ipamorelin, selank, kisspeptin-10, LL-37, melanotan II, PEG-MGF, dihexa, thymosin alpha-1, or AOD-9604.
Absence from the list is not a new ban printed in this notice. It means the Oct 28 sentence does not cover them. Whatever status they had on Oct 27 is the status to check. Are peptides legal? keeps those categories, including the July 2026 vote that did not recommend DSIP.
A few that get mixed in on purpose:
Selank is not semax.
Thymosin beta-4, the longer protein, is not the TB-500 fragment Appendix B prints.
Injectable GHK-Cu is not KPV.
Sermorelin is a different peptide with its own history. It is not one of these six. See Sermorelin is not one of the six.
What a similar story online does not prove
"It was at the same meeting" is not "it is in Appendix A." The July advisory committee voted on seven peptides and recommended six. DSIP was the one it did not recommend, as our legal explainer records. This October policy tracks those six, not the seventh [2].
Future rulemaking may propose adding some or all of the six to the 503A bulks list [1]. That sentence is about the peptides already in the policy. It is not a promise about the ones left off.
FAQ
Did everything that left Category 2 in April get this policy? No. April removals were a longer list. Appendix A is six names [2].
If my peptide is not listed, did HHS say it is prohibited? This notice does not say that. It withholds this discretion. Check that peptide's own status [1].
Sources
HHS notice, FR Doc. 2026-22192, filed Oct 28, 2026. https://public-inspection.federalregister.gov/2026-22192.pdf
HHS policy, Appendix A. https://www.hhs.gov/sites/default/files/hhs-503a-peptide-enforcement-discretion-policy-appendix-b.pdf
Sommar Club does not prescribe or sell the six, or the other peptides named above. Education only. Not medical or legal advice. As of Oct 29, 2026.
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